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Co-occurring Conditions

Features of neurodiversity can be highly variable and complex due to underlying genetic contributors, medical concerns, and psychological diagnoses. As such, neurodivergent individuals can (and do) often experience co-occuring conditions, including autism, Fragile X syndrome, Rett Syndrome, Attention Deficit/Hyperactivity Disorder (ADHD), depression, anxiety, intellectual disability, schizophrenia, epilepsy, functional neurological disorder, gastrointestinal (stomach) issues, and susceptibility to infections [1,2]. 

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Below describe two studies that explored large datasets on co-occurring conditions in autistic individuals. The first, Salehi et al. [1] describes the youth experience (children aged 3-17 years) and the second, Jadva and Bal [2] describes the adult experience (adults aged 18-85 years).

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Youth Experience 

Salehi et al. [1] examined data from the National Survey of Children’s Health (NSCH) which collected data on children/youth aged 3-17 years for the years 2020–2021. The dataset consisting of 93,669 participants, of which 2,568 individuals (or 3.2%) had a confirmed current diagnosis of autism. They found that 96.4% of youth with autism had at least one co-occurring condition:

  • The most common psychological co-occurring diagnoses were developmental delay (64%), then behavioral and conduct problems (57.8%) and anxiety problems (45.7%); see blue arrows in Figure 1 below

  • The most common medical co-occurring diagnoses were allergies (32.4%), genetic disorders (26.2%), and asthma (12.6%); see blue arrows in Figure 2 below

  • The odds of co-occurring vision problems, cerebral palsy, frequent/severe headaches, epilepsy, depression, and intellectual impairment were significantly greater in females than males, whereas ADHD and anxiety were significantly lower among females with autism [1]

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Figure 1: Psychological Conditions

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Green bars represent youth (3-17) who are diagnosed with autism and red bars represent youth that are not diagnosed with autism

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Figure 2. Medical Conditions

Screenshot 2024-12-15 at 4.07.59 PM.png

Green bars represent youth (3-17) who are diagnosed with autism and red bars represent youth that are not diagnosed with autism

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Adult Experience 

 

Jadav et al. [2] examined data from the SPARK dataset (SPARK = Simons Powering Autism Research Knowledge) in which autistic adults completed a medical questionnaire to indicate which psychiatric and medical conditions they have experienced. In total, 4657 autistic adults provided data (age range was 18-85 years) 

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Below is a data that summarizes the psychiatric and medical conditions endorsed by the complete sample (all), with information also shown for autistic adults under age 40 and over age 40 [2]

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The data in the table are sorted with the most common condition (for the all ages column) appearing at the top and the least endorsed condition appearing at the bottom. The top three most commonly experiencing co-occuring conditions were anxiety disorders (other than social anxiety) at ~56%, depression at ~53%, and ADHD at 44%

 

Note that the top 3 conditions are also true for the 18-39 age group, but are different with the 40+ age group, with depression at first with ~53%, followed by anxiety disorder at ~48%, and then ADHD at ~37% [2]

Autism is Multi-Layered.jpg

For more information on a co-occurring condition, click one of the following 

References

1. Mona Salehi, M.,  Ahmad, A., Lot, A., &   Gunturu, S. (2024). Characteristics and co-morbidities of Autism Spectrum Disorder as risk factors for severity: A national survey in the United States. Research Square, preprint. https://www.researchsquare.com/article/rs-3921934/v1

 

2. Jadva, N., & Bal, V. H. (2022). Associations between co-occurring conditions and age of autism diagnosis: Implications for mental health training and adult autism research. Autism Research, 15, 2112-2125. https://doi.org/10.1002/aur.2808

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